Cherokee County is the westernmost County in North Carolina on the border with Georgia to the south and Tennessee to the west near Chattanooga.

The County is within 2 hours or less of Atlanta via US 19/129 or US 60; Chattanooga, Tennessee via US 74; Knoxville, Tennessee via US 129 & US 321; Greenville/Spartanburg, SC via US 76 & US 123; and Asheville, NC via US 74 & I-40.

In addition, the Cherokee County is within two hours or less of has convenient access to several major interstates including I-40, I-85, I-26, I-75, and I-40 – all major US trade routes. A location in Cherokee County means that your company is within a single day’s drive to over 60% of the U.S. population and within a half-day’s drive to the major east coast seaports of Charleston, SC and Savannah, Ga.


Corporate Aircraft
Corporate aircraft have the ability to utilize the Western Carolina Regional Airport located in Andrews, NC.  WCRP is a county-owned public-use airport located two miles west of the central business district of Andrews and has a 5,500-foot runway that can accommodate most corporate aircraft.

International Airport Access

Cherokee County residents have access to one of the busiest and most efficient international airports in the world in Atlanta’s Hartsfield Jackson International Airport. Located just over two hours from Cherokee County, Hartsfield-Jackson International offers hundreds of daily domestic flights and dozens of international flights. For more information visit: Hartsfield-Jackson Atlanta International Airport.

Cherokee County is also within 2 hours or less of three regional airports:


Companies that utilize ports are within a 6-hour drive of two of the nation’s major seaports – the Port of Charleston and the Port of Savannah; and within 2-hours of the Port of Chattanooga on the Tennessee River with access to the Gulf of Mexico.

The Port of Charleston is a six hour drive from the County seat of Murphy and is accessed via US 74 to I-26 which connects directly to the port.   For additional information on the Port of Charleston visit the port’s website at:

The Port of Savannah is also within a 6-hour drive of Cherokee County and is approximately 370 miles away. For additional information on the Port of Savannah visit the port’s website at:

The Tennessee Tombigbee Waterway System can serve customers that require access to or from the Gulf of Mexico at the Port of Mobile.   There is a port in the system in nearby Chattanooga which is approximately 2 hours from Cherokee County. For more information visit the Tennessee Tombigbee website at:


The Great Smoky Mountain Railway provides tourism and freight service to portions of Cherokee County.  The rail line could be accessible to business and industry via the Andrews to Murphy line which connects to industrial served lines in Bryson City and on to Asheville, NC where it connects with Norfolk-Southern. The NC Department of Transportation owns the rail line and conducted a study of the line in 2015 that includes recommendations to make improvements to the line to service industrial customers.   For more information visit:

Cherokee County North Carolina Economic Development Corporation